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Feline Special Offer:
8 cat DNA tests for just £79.95 including VAT
HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups

new test: Mycobacterium Avium Complex ( MAC ) sensitivity in Miniature Schnauzer
new test: Chondrodystrophy (CDDY with IVDD Risk) and Chondrodysplasia (CDPA) in many breeds ...
new test: Lafora Disease (LAF)/ Myoclonic Epilepsy in Basset Hound, Beagle, Chihuahua and Mini Wirehaired Dachshund
new Kennel Club DNA testing schemes with LABOKLIN:
• Sensory Neuropathy in Border Collie
• Neuroaxonal Dystrophy ( NAD ) in Papillon


Coat colour Variant Agouti (Tabby)

Test number: 8090

Breed
All Cat Breeds .
Description

The Agouti (agouti signalling protein, ASIP) gene produces a protein that regulates the distribution of black pigment (eumelanin) within the hair shaft. The wild type allele A is dominant and produces hair shafts with alternating bands of yellow and black color, ending with black tips (similar to the coat of a wild mouse or rabbit). The recessive allele a produces a cat that is self-colored (solid) when 2 copies of a are present. Another system of pigmentation in cats produces the tabby patterns of dark stripes interspersed with the lighter agouti tipped hairs. Hairs in the darker stripes do not have the shift between black and yellow pigment production and remain uniformly dark. The effect of the agouti protein on orange pigment is limited, thus tabby striping may still be seen on cats that are a/a for agouti.

A/A: Homozygous for agouti. All offspring will have agouti banded hair.

A/a: Heterozygous for agouti. Offspring can be agouti or non-agouti depending on the genetics of the mating.

a/a: Homozygous for non-agouti (solid colored). If bred to a non-agouti, only non-agouti offspring will be produced.

How does the genetic test work and how safe is it?

Firstly, the DNA which is the genetic information of an animal is isolated from a blood or a cheek swab sample. Then the genes of interest are amplified a million-fold by PCR (polymerase chain reaction) to facilitate the following analysis. The analysis is automatically performed by a genetic analyzer and reveals the gene sequence of the region of interest.

Therefore, the mutations leading to the different coat colours can be seen directly and heterozygous carriers of these mutations can also be identified. Since the test is done mainly automatically, laboratory errors can be widely excluded.

Interpretation of the test results

The test results will be submitted separately for each coat colour, so that the genotype for each corresponding gene locus will be given.

Sample Requirements
Whole blood in EDTA tube (0.5 - 1 ml) or Buccal Swabs. Whole blood in EDTA tube (0.5 - 1 ml) or Buccal swabs. .
Turnaround
1 - 2 weeks
Price
Number of Coat Colour Tests on the same cat Price (including VAT)
First Colour test £ 48.00
Each additional colour test on the same cat £ 24.00

To order:

  • Download Order Form from this link pdf

  • Complete the order form and send it together with your samples to the following address:

    Laboklin (UK),   125 Northenden Road, Manchester, M33 3HF

See Also:
Coat Colour cinnamon  
Curly Coat  
Coat Colour variant Siamese (Point)  
Coat Colour Burmese brown  
Coat Colour DILUTION  
Coat Length  
Coat Colour Charcoal  
Coat colour amber  
Coat Colour Albino  
Dominant White / White Spotting  
Sphynx / Devon Rex  
Coat Colour: Snow  
Coat Colour: Chocolate and Cinnamon  
Colourpoint Siamese and Burmese ( Siamese , Burmese and Mink )  
Feline Coat Colours OFFER: Agouti + Burma + Chocolate + Cinnamon + Dilution + Siam  
Bengal Colours OFFER: Charcoal + Chocolate + Cinnamon + Snow + Dilution  
Russet Coat Colour  
Coat Colour chocolate  

 
 
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LABOKLIN GmbH & Co. KG
ISO / DIN 17025 Accredited Laboratory
© 2007 Laboklin (UK)
125 Northenden Road, Manchester, M33 3HF
Tel. 0161 282 3066