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Crufts 2022   Home   News and offers   Genetic Diseases   Coat Colours / Length   Identity / Parentage   Reptiles & Amphibians   Avian Tests   Profiles / Screening   Infectious Diseases   Organs / Parameters   Allergy testing   Pathology   Downloads & Order   Order Kit Online   About Us   Crufts & Shows Supreme Cat Show 2024 Crufts 2024 Supreme Cat Show 2023 Crufts 2023 Supreme Cat Show 2022 Crufts 2022 Crufts 2020 Supreme Cat Show 2019 Crufts 2019 Crufts 2018 Crufts 2017 Crufts 2016 Crufts 2015 Crufts 2013 Crufts 2014 MCR Pet Show 2013 Crufts 2012 UK National Dwarf GSD   Contact Us   Kennel Club ABS   facebook   **NEW** Maine Coon Special offer: 8 DNA tests for just £84.95 incl VAT Maine Coon 8 DNA tests bundle (HCM, SMA, PKDef, Poly, b, b1, cb, cs)  **NEW** Bengal Special offer: 4 Bengal Specific DNA tests for just £72.00 incl VAT Bengal DNA bundle (rdAc-PRA + b-PRA + PK-Def + Blood Groups)  British Special offer: 4 Breed Specific DNA tests for just £72.00 incl VAT British Short / Long Hair DNA bundle (PKD + pd-PRA + ALS + Blood Groups) Burmese Special offer: 4 Breed Specific DNA tests for just £72.00 incl VAT Burmese DNA bundle (Hypokalemia (BHK) + Head Defect + Gangliosidosis (GM2) + Blood Groups Birman Special offer: 5 Breed Specific DNA tests for just £72.00 incl VAT Birma DNA bundle (PKD + pd-PRA + Hypotrichiose + MPS6 + Blood Groups) Maine Coon Special offer: 5 Breed Specific DNA tests for just £72.00 incl VAT Maine Coon DNA bundle (HCM1 + SMA + PK-Def + F11 + Blood Groups) Ragdoll Special offer: 5 Breed Specific DNA tests for just £72.00 incl VAT Ragdoll DNA bundle (HCM1 + HCM3 + PKD + pd-PRA + Blood Groups) Norwegian Special offer: 4 Breed Specific DNA tests for just £72.00 incl VAT Norwegian Forest DNA bundle (PK-Def + Amber + GSD4 + Blood Groups) Feline Special Offer: 8 cat DNA tests for just £84.95 including VAT HCM, HCR, GSD4, PKD, PRA, PK-Def., SMA, Blood Groups you can view this email in browser click here February 2022     LABOKLIN NEWS   LABOKLIN AT CRUFTS 2022 10th - 13th March Dear Breeder We are pleased to announce that LABOKLIN will be at Crufts from 10th to 13th March 2022 and we look forward to seeing you there. Our stand is located in Hall 3 opposite the restaurant, it is stand number 3-7a as shown in the diagram. Meet the Laboklin UK team in person We are always talk to you on the phone, by email or even via facebook, however, at Crufts we are very excited to meet you in person and to answer any questions you have, please stop by and say hi. Crufts offer 10% discount on all DNA tests submitted at Crufts! and this offer includes our Breed Specific DNA Bundles and the brand new KC breed bundles How to submit a sample at Crufts: How to submit a sample at Crufts : Bring your dog to our stand 3-7a: we will take a DNA sample for your genetic test, all you need to do is complete the order form and pay the fees. Or, If you don't want to wait in the queue, you can prepare your sample in advance and bring it together with the attached order form with you to our stand. You can order a free DNA testing kit on our website, click on the following link to order: Request sample materials We will send you a testing kit which also contains order form and instructions on how to take DNA sample from the mouth. Prepare your sample up to a week before your planned visit, just hand the sample to us at the show. If you prefer to use  blood for your test, ask your vet to collect 0.5-1 ml of whole blood in EDTA blood tube, bring it together with the completed order form to the show, just hand it to us. (you can order free EDTA blood tube from our website http://www.laboklin.co.uk ) Please note we will only accept Cash, Cheques or Postal Orders at the show. If you wish to pay by card, you can complete the card payment section on the order form. Paypal payments must be made in advance. Turnaround: 1-3 weeks for the majority of tests from Monday 14th March.  The attached order form will only be accepted at Crufts 2022. If you have any questions, please email info@laboklin.co.uk or ring 0161 2823066. We look forward to seeing you at Crufts. Kind regards The Laboklin Team LABOKLIN (UK) Laboratory For Veterinary Diagnostics 125 Northenden Road Manchester M33 3HF   Tel: 0161 282 3066 Fax: 0161 973 3434 www.laboklin.co.uk www.facebook.com/Laboklin Feb 2022 Newsletter PDF Download Crufts 2022  Order Form PDF Download new Progressive Retinal Atrophy (JPH2 - PRA ) in Shih Tzu   Progressive retinal atrophy (PRA), common autosomal recessive disorder affecting several dog breeds including Shih Tzu, is characterized by degeneration of photoreceptors leading to blindness. A mutation in the JPH2 gene has been identified to be responsible for PRA in the Shih Tzu breed and the test is now available at Laboklin. cost £48.00 more informatrion is available on the following link: JPH2 - PRA in Shih Tzu new Exfoliative Cutaneous Lupus Rrythematosus ( ECLE ) / Lupoid Dermatosis in German Shorthair Pointer , Hungarian Vizsla , Hungarian Wirehaired Vizsla (Vizslak) . Exfoliative Cutaneous Lupus Erythematosus (ECLE), which is also known as Lupoid Dermatosis is an inherited monogenic (controlled by one gene) disease that has been observed in the German Shorthaired Pointer and Hungarian Vizsla breeds. Symptoms start in the first year of age and include skin lesions, lameness, scaling, erythema (reddening of the skin), erosions/ulcers, scarring, disfiguration, decreased quality of life, progresses to joint pain, oligospermia (low sperm count) in males which progressed to azoospermia (absence of sperm), irregular heat cycles in females. Dogs with this disease have dramatically shortened life expectancies and are generally humanely euthanized upon diagnosis. The mode of inheritance is autosomal recessive, which means that the disease occur when the puppy inherits two copies of the mutation, one from each parent. cost £48.00 more informatrion is available on the following link: Exfoliative Cutaneous Lupus Rrythematosus ( ECLE ) new Dilated Cardiac Myopathy (DCM) in Doberman, Schnauzer and Welsh Springer Spaniel The disease is characterized by a swelling of one or both of the hearts ventricles (lower chambers) which weakens the ability of the heart to pump blood and consequently the heart becomes larger and the beats become weaker. Symptoms can vary in the different breeds. Some affected dogs may not exhibit any visible signs and yet die suddenly without warning, or may not show any symptoms for years, however, eventually, start exhibiting symptoms of ill health including: lethargy, loss of appetite, coughing especially during exercise, gasping for breath, fainting or collapsing and progressive abdominal swelling. Although these signs can signify the onset of heart failure, they are also shared with other conditions and therefore testing is vital for the diagnosis. In Schauzer the disease is caused by a mutation in the RBM20gene, In Welsh Springer Spaniel it is caused by a mutation in the PLN-gene, whereas is Doberman it can be caused by a mutation in the PDK4 gene, and / or mutation in the TTN gene. cost £48.00 each more informatrion is available on the following links: Dilated Cardiomyopathy (DCM) in Giant Scnauzer Dilated cardiomyopathy (DCM) in Welsh Springer Spaniel Dilated cardiomyopathy DCM1 (PDK4) in Doberman Dilated cardiomyopathy DCM2 (Titin) in Doberman Dilated cardiomyopathy bundle DCM1 + DCM2 in Doberman new CNS Atrophy with Cerebellar Ataxia (CACA) in Belgian Shepherd Dog (Malinois)   Our cooperation partner Prof. Tosso Leeb and his team from the University of Bern have identified a new genetic variant causing a neurological disease called CNS atrophy and cerebellar ataxia (CACA) in the breed Belgian Shepherd. Affected puppies show uncoordinated movements, intention tremor, short episodes of spastic fits, general elevated muscle tone and a reduced swallowing reflex. Moreover, affected puppies show less body weight increase as their unaffected littermates. First signs could be observed at the age of about 2 weeks. However, the severity of the signs are highly variable. Many affected puppies have to be euthanized a few weeks after the first signs whereas an affected dog with less intense symptoms has been reported to become up to 10 years old. cost £48.00 each more informatrion is available on the following link: CNS Atrophy with Cerebellar Ataxia (CACA) new Macular Corneal Dystrophy ( MCD / CHST6 ) in Labrador Retriever Macular Corneal Dystrophy (MCD) is an inherited eye disease affecting humans and dogs. The disease characterized by progressive diffuse cloudiness of the cornea and the presence of grayish-white spots in the superficial corneal stroma. The disease is caused by a mutation in the CHST6 gene which causes abnormal accumulation of complex carbohydrates called glycosaminoglycans in the cornea, mainly in the keratocytes and the corneal epithelium. Clinical symptoms are usually seen in affected middle aged dogs, and include: Visual impairment, corneal cloudiness, grey-white spots of various sizes on the cornea, blood vessels maybe seen across the corneal surface, increased intensity of the corneal cloudiness and loss of visual acuity. This mutation has only been reported in Labrador Retrievers, but may be found in Labrador-cross breeds. Treatment: in dogs there is no treatment. In human, this is treated by corneal transplant. The test is part of the Kennel Club DNA testing scheme in Labrador Retriever cost £48.00 each more informatrion is available on the following link: Macular Corneal Dystrophy ( MCD / CHST6 ) new Ichthyosis Type 2 in Golden Retriever Ichthyosis type 2 is another variant which causes Ichthyosis in Golden Retriever, this test helps in explaining cases which was tested negative for the already known Ichrthyosis variant. Ichthyosis is a genetic disease causing dysfunction of the keratin in the skin, which leads to the production of large, differently pigmented skin scales. Due to the fish-like look of this scales the name was formed from the Greek word for fish: "Ichthys". Additionally, the pigmentation of the skin can be altered. Dogs which are affected by this dermatosis develop first symptoms soon after birth. Unfortunately, there is no treatment for this disease. In some cases, formation of scales decreases in old dogs.   cost £48.00 each more informatrion is available on the following link: Ichthyosis type 2 (ICH 2) in Golden Retriever Progressive Retinal Atrophy (PRA) more variants identified and more breeds affected The following Progressive retinal atrophy (PRA) tests have recently been added: Progressive Retinal Atrophy (JPH2 - PRA)in Shih Tzu Progressive Retinal Atrophy (crd3-PRA) in Glen of Imaal Progressive Retinal Atrophy (PRA4) in Lhasa Apso IFT122-PRA (IFT 122 PRA) in Lapponian Herder Progressive retinal atrophy (PRA3) in Tibetan Terrier & Tibetan Spaniel Progressive Retinal Atrophy Early Onset (EO-PRA) in Spanish and Portuguese Water dogs Stargardt disease (STGD) in Labrador Retriever Pituitary Dwarfism has been identified in Tibetan Terrier the test is now valid for the following breeds: Czechoslovakian Wolfdog, German Shepherd, Karelian Bear Dog, Lapland Reindeer Dog, Lapponian Herder, Saarloos Wolfdog, Tibetan Terrier, White Swiss Shepherd Inherited Dwarfism is a condition in which the production of the Growth Hormone (GH) is inadequate. Growth hormone is secreted by the pituitary gland and has many effects on the body including control of growth rate, maintenance of hair coat, and bone and teeth development. Affected dogs appear normal at birth, but show evidence of failure to grow by two to three months of age. Symptoms include small stature compared to littermates, retention of puppy coat, hair loss, darkening of the skin, delayed eruption or absence of permanent teeth, a shrill bark, Small testicles and sometimes infertility in the male, Absence of heat and sometimes infertility in the female. Affected dogs appear normal at birth, but show evidence of failure to grow by two to three months of age. Symptoms include small stature compared to littermates, retention of puppy coat, hair loss, darkening of the skin, delayed eruption or absence of permanent teeth, a shrill bark, Small testicles and sometimes infertility in the male, Absence of heat and sometimes infertility in the female. The test is part of the Kennel Club DNA testing scheme in Tibetan Terrier cost £48.00 each more informatrion is available on the following link: Dwarfism (Pituitary Dwarfism / Hypopituitarism) new Chihuahua DNA bundle the most relevant tests for the breed in one submission Chondrodystrophy (CDDY with IVDD Risk) and Chondrodysplasia (CDPA) Macrothrombocytopenia ( MTC-D ) Neuronal Ceroid Lipofuscinosis ( CL / NCL ) Progressive Retinal Atrophy (prcd-PRA): (8094P / 8127) cost £138.00 each more informatrion is available on the following link: Chihuahua DNA bundle new Giant Schnauzer DNA bundle the most relevant tests for the breed in one submission   Degenerative Myelopathy / Degenerative Radiculomyelopathy) DM (Exon 2) Dilated Cardiomyopathy ( DCM ) Hyperuricosuria / Urate Stones (HUU, SLC) NECAP-1 Progressive Retinal Atrophy ( NECAP1 PRA / NECAP PRA5) KC* DNA scheme in Giant Schnauzer Progressive Retinal Atrophy (prcd-PRA): (8094P / 8127) KC* DNA scheme in Giant Schnauzer cost £156.00 more informatrion is available on the following link: Giant Schnauzer DNA bundle new Russian Black Terrier DNA bundle the most relevant tests for the breed in one submission   Degenerative Myelopathy / Degenerative Radiculomyelopathy) DM (Exon 2) Hyperuricosuria / Urate Stones (HUU, SLC) KC* DNA scheme in Russian Black Terrier (RBT) Juvenile Laryngeal Paralysis & Polyneuropathy (JLPP) KC* DNA scheme in Russian Black Terrier (RBT) cost £138.00 more informatrion is available on the following link: Russian Black Terrier DNA bundle new Yorkshire Terrier DNA bundle the most relevant tests for the breed in one submission   Chondrodystrophy (CDDY with IVDD Risk)and Chondrodysplasia (CDPA) L-2-HGA ( L- 2 - hydroxyglutaric aciduria ) L2HGA Primary Lens Luxation (PLL) Progressive Retinal Atrophy (prcd-PRA): (8094P / 8127) Subacute Necrotizing Encephalopathy (SNE) cost £156.00 more informatrion is available on the following link: Yorkshire Terrier DNA bundle new Bulldog DNA bundle the most relevant tests for the breed in one submission Degenerative Myelopathy / Degenerative Radiculomyelopathy) DM (Exon 2) Hyperuricosuria / Urate Stones (HUU, SLC) KC* DNA scheme in Bulldog (English) Cystinuria type III Canine Multi-Focal Retinopathy (CMR) cost £138.00 more informatrion is available on the following link: Bulldog DNA bundle new Tibetan Terrier DNA bundle Neuronal Ceroid Lipofuscinosis ( CL / NCL ) KC* DNA scheme in Tibetan Terrier Primary Lens Luxation (PLL) KC* DNA scheme in Tibetan Terrier Progressive retinal atrophy ( rcd4-PRA) / LOPRA KC* DNA scheme in Tibetan Terrier Degenerative Myelopathy / Degenerative Radiculomyelopathy) DM (Exon 2) Dwarfism (Pituitary Dwarfism / Hypopituitarism) KC* DNA scheme in Tibetan Terrier cost £156.00 more informatrion is available on the following link: Tibetan Terrier DNA bundle new Irish Red & White Setter DNA bundle CLAD (Canine Leukocyte Adhesion Deficiency) Globoid Cell Leukodystrophy (Krabbe Disease) von Willebrand disease Type I (vWD I) KC* DNA scheme in Irish Red and White Setter Progressive Retinal Atrophy (rcd1 PRA) Progressive retinal atrophy ( rcd4-PRA) / LOPRA cost £138.00 more informatrion is available on the following link: Irish Red & White Setter DNA bundle new Labradoodle DNA bundle Degenerative Myelopathy / Degenerative Radiculomyelopathy) DM (Exon 2) Exercise Induced Collapse ( EIC ) Hereditary Nasal Parakeratosis (HNPK) Dwarfism (Skeletal Dysplasia 2 / SD2 ) Neonatal encephalopathy (NE / NEWS) von Willebrand disease Type I (vWD I) Hereditary Myopathy / Centronuclear Myopathy (HMLR, CNM) Progressive Retinal Atrophy (prcd-PRA): (8094P / 8127) Progressive retinal atrophy ( rcd4-PRA) / LOPRA cost £240.00 more informatrion is available on the following link: Labradoodle DNA bundle new Kennel Club DNA testing schemes The following tests are now part of the Kennel Club DNA testing schemes: Stargardts disease (STGD) in Labrador Retriever more .. Macular Corneal Dystrophy (MCD) in Labrador Retriever more .. X-linked PRA Type 1 (XL-PRA1) in Samoyed more .. Hereditary Nephritis / X-linked (XLHN) in Samoyed more .. Copper Toxicosis (COMMD1) in Bedlington Terrier more .. Pituitary Dwarfism in Tibetan Terrier more .. Leukoencephalomyelopath (LEMP) in Rottweiler more .. Raine?s syndrome/ Dental hypomineralisation in Border Collie more .. Amelogenesis Imperfecta / Familial Enamel Hypoplasia (AI/FEH) in Japanese Akita Inu more .. PRA (prcd-PRA) in American Cocker Spaniel and Barbet more .. CNGA1 - PRA in Shetland Sheepdog more .. vWD type 1 in Papillon (Continental Toy Spaniel) more .. Primary Open Angle Glaucoma (POAG) in Norwegian Elkhound more .. Dwarfism (Chondrodysplasia / disproportinate short-limbed) in Norwegian Elkhound. more .. NECAP1 PRA / NECAP PRA5 in Giant Schnauzer more .. testing is easy To test a dog, we need a DNA sample, which can be collected using simple mouth swabs or a blood sample collected by the vet. Both buccal swabs and blood tubes are available from us free of charge. Samples can be sent to our Manchester address below. Turnaround 2-3 weeks or sooner for most DNA test. Request Sample Materials LABOKLIN is a DIN EN ISO / IEC 17025 Accredited laboratory. This means that all our tests are performed according to the reliable accreditation standards and verified procedures. Stay up to date with all the news and special offers by visiting our facebook page If you no longer wish to receive mail from us, you can   unsubscribe LABOKLIN (UK), 125 Northenden Road, Manchester, Greater Manchester, M33 3HF, United Kingdom

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Unit 20, Wheel Forge Way, Trafford Park, Manchester, M17 1EH

Tel. 0161 282 3066