LABOKLIN VETERINARY DIAGNOSTIC LABORATORY (UK & Ireland)

What a great place to share the latest news with our customers, we will post information about new tests, schemes, events, discounts and will be able to answer many of your queries.

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LABOKLIN will be at the Manchester Pet Show on 7th & 8th September 2013.

10% Discount on all genetic tests submitted at the show (Except partner lab tests such as Optigen).

Our stand number is 134 opposite the Kennel Club stand.

We would love to see you there, whether you want to submit a sample, to chat or just to say hello, we will be pleased to see you.

Yes ... all tests including canine, feline, equine and avian ...

How to submit a sample at Manchester Pet Show:

1) Bring your animal to our stand 134, we will take a DNA sample for your genetic test, all you need to do is complete the order form and pay the fees. Or,

2) If you don't want to wait in the queue, you can prepare your sample in advance and bring it together with the attached order form with you to our stand, you can order a free DNA testing kit on our website, click on the following link:

Request sample materials

We will send you a testing kit which also contains order form and instructions on how to take DNA sample from the mouth. Prepare your sample up to a week before your planned visit, just hand the sample to us.

3) If you prefer to use blood for your test, ask your vet to collect 0.5-1 ml of whole blood in EDTA blood tube, bring it together with the completed order form to the show, just hand it to us. (you can order free EDTA blood tube from our website https://www.laboklin.co.uk )

Please note we will only accept Cash, Cheques or Postal Orders at the show (no cards). Paypal payments must be made in advance.

Turnaround: 7 working days from Monday 9^th September.

LABOKLIN is now official Optigen partner.

For customers who would like send samples to Optigen in USA, you can now send your samples to our Manchester address and we will do everything else ... and where a Kennel Club DNA Testing Scheme is in place, results will also be recorded by the KC.

NEW TESTS

Protein Losing Nephropathy (PLN) in Soft Coated Wheaten Terrier:

Protein Losing Nephropathy (PLN) is an inherited disease that affect Soft-Coated Wheaten Terriers and results in essential proteins being lost through the kidney. The disease can be mild and stable for years, however, it may lead to severe complications including kidney failure. Progression of the symptoms is variable and often influenced by environmental factors.

Diagnosis of PLN has always been difficult, especially in the early stages of the disease, it can be misdiagnosed as liver, gland or other kidney diseases. Thanks to advances in molecular biology, teh mutation associated with PLN has been identified and Laboklin can now offer a DNA testfor PLN in Soft-Coated Wheaten Terriers.

Primary Ciliary Dyskinesia (PCD) in Old English Sheepdog (Bobtail):

Primary Ciliary Dyskinesia (PCD) is an autosomal-recessive genetic disease characterized by recurrent infections of the respiratory tract as well as reduced male fertility. Around 50% of the affected dogs develop situs inversus (Kartagener syndrome). The underlying cause is a motility defect in the respiratory cilia responsible for airway clearance and in the flagella responsible for propelling sperm cells.

Bull Terrier Polycystic Kidney Disease (BTPKD):

Polycystic Kidney Disease is a genetic slow progressing and irreversible disease characterised by the presence of cysts in the functional areas of the kidneys, The size of the cysts varies from 0.5 mm to 2.5 mm. Cysts grow and expand replacing the normal kidney tissue, as a result, the functionality of the kidneys declines, the disease is likely to end with chronic renal failure in middle to old aged dogs. The disease affects both kidneys.

Clinical symptoms may not appear in the early stages of the disease but it will appear when the disease progresses, signs include excessive water drinking, loss of appetite, increased urination, weight loss, sporadic vomiting and depression.

BTPKD is an autosomal dominant disease with high penetrance, this means that positively affected dogs are highly likely to develop the disease.In this mode of inheritance, dogs who carry only one copy of the mutant gene are likely to develop the disease.

Up until recently BTPKD was diagnosed using renal ultrasonography, however, now a DNA test is available at LABOKLIN, using a simple mouth swabs or blood sample it is possible to identify genetically affected dogs from very young age.

Late Onset Ataxia (LOA) in Parson Russel Terrier (PRT):

Late onset ataxia (LOA) in the Parson Russell Terrier is a genetic disease characterised by progressive gait incoordination and loss of balance. Early symptoms are usually seen at the age of 6-12 month, the disease progresses, gait becomes increasingly incoordinated with difficulty in moving around or complete loss of mobility. This disease is caused by a mutation in the calcium activated neutral proteinase 1 (CAPN1)-gene.

Pompe's Disease (Glycogen Storage Disease type II / GSDII) in Finnish Lapphund, Lapponian Herder and Swedish Lapphund:

Pompe's disease or GSDII (Glycogen Storage Disease Type II) is caused by deficiency of the acid alpha-glucosidase enzyme which leads to accumulation of glycogen in the cells, and this results in abnormal glucose levels in tissues such as cardiac, skeletal, and smooth muscle.

Affected dogs suffer from vomiting, regurgitation, progressive muscle weakness, exercise intolerance and heart problems. Symptoms start at around seven month of age, affected dogs usually die around 1.5-2 years of age.

Cobalamin Malabsorption (Imerslund-Gr�sbeck syndrome (IGS)) in Beagle and Border Collie:

Cobalamin malabsorption (merslunf-Gr�sbeck Syndrome (IGS)) refers to a genetic disorder by which the vitamin B12, also known as cobalamin, fails to be absorbed from the intestine. Lack of cobalamin leads to changes in the hematopoietic system and to neurological symptoms due to irreversible damage of the brain and nervous system. Symptoms include anorexia, lethargy and failute to gain weight. Cobalamin malabsorption can be managed by supplementation with regular doses of cobalamin.

GM1-Gangliosidosis in Huskies, Portuguese Waterdog and Shiba Inu:

GM1-Gangliosidosis is a lysosomal storage disease that leads to neurological disorders. Affected dogs suffer from paralysis of the extremities and spasticity of the muscles. At the age of about 8 months most dogs die of this disease.

NEW BREEDS ADDED TO EXISTING TESTS

Cavalier King Charles Spaniel can now be tested for Muscular Dystrophy (MD):

Muscular Dystrophy (MD) was only valid for Golden Retriever but now Cavalier King Charles Spaniel has been added to the affected breed list.

Muscular Dystrophy (MD) is a spontaneous, X-linked, progressively fatal disease of dogs and is also a homologue of Duchenne muscular dystrophy (DMD). Affected dogs show raised creatine kinase levels, muscle atrophy with contractures, hyaline myofiber degeneration with mineralization, endomysial and perimysial fibrosis with fatty infiltration, and cardiomyopathy.

American Staffordshire Terrier can now be tested for Neuronal Ceroid Lipofuscinosis (NCL):

Neuronal Ceroid Lipofuscinosis (NCL) was offered for Australian Shepherd , Border collie , Dachshund , Miniature Long Haired Dachshund , Miniature Smooth Haired Dachshund , American Bulldog , English Setter and Tibet Terrier breeds, now American Staffordshire Terrier has been added to the list.

NCL's clinical symptoms include increasing levels of agitation and possible outbursts of aggression, hallucinations, hyperactivity and epileptic fits. Most animals lose their ability to coordinate everyday muscular activities. As the extent of neurodegeneration increases, all affected dogs develop psychological abnormalities and ataxia.

LABOKLIN acquires Exclusive Worldwide License to offer Hereditary Nasal Parakeratosis (HNPK) in Labrador Retriever

Hereditary Nasal Parakeratosis a genetic disorder that causes the dog's nose to dry, especially, the upper surface of the planum forms keratinous scales, which adhere to the nose. Bloody fissures might occur in this structures, leading to chronic irritation and inflammation of the noses skin. The colour of the skin might change from dark to lighter colour. Affected dogs develop first symptoms at the age of six month to one year. The nose can be treated with Vaseline, propylene glycol or salicylic acid containing products to ease the symptoms.

The price of Alaskan Malamute Polyneuropathy (AMPN / IPAM / HPAM) reduced to �55.00

	prices in Pound

MCR Pet Show 2013