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Supreme Cat Show 2022 |
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October
2022
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Laboklin
at the
GCCF Supreme Cat Show
Saturday 22nd October 2022
Kenilworth, Warwickshire CV8
2LZ
10 %
Show Discount
on
samples submitted at the show
Dear Breeder
We are pleased to announce that LABOKLIN will be at the GCCF Supreme Cat Show on Saturday 22nd October 2022 and we look forward to seeing you there.
Meet the experts
We are pleased to announce that our feline genetics expert Nadine Gänstaller
will be at the show and will be very pleased to answer any questions or queries you have.
We always talk on the phone, by email or even via facebook, however, at the GCCF we are very excited to meet you in person and to answer any questions you have, please stop by and say hi.
The Show offer
10% discount on all DNA tests submitted at the GCCF Supreme Cat Show! and this offer includes our Breed Specific DNA Bundles which are already heavily discounted.
How to submit a sample at the GCCF show:
- Bring your cat to our stand: we will take a DNA sample for your genetic test, all you need to do is complete the order form and pay the fees. Or,
- If you don't want to wait in the queue, or if you are attending the show without your cats, you can prepare your sample in advance and bring it together with the attached order form with you to our stand. You can order a free DNA testing kit on our website, click on the following link to order:
Request sample materials
We will send you a testing kit which also contains
order form and instructions on how to take DNA sample from the mouth. Prepare your sample up to a week before your planned visit, just hand the sample to us at the show.
- If you prefer to use blood for your test, ask your vet to collect 0.5-1 ml of whole blood in EDTA blood tube, bring it together with the completed order form
(click
here to download the show discounted form) to the show, just hand it to us. (you can order free EDTA blood tube from our website http://www.laboklin.co.uk )
Please note we will only accept Cash, Cheques or Postal Orders at the show. If you wish to pay by card, you can complete the card payment section on the order form. Paypal payments must be made in advance.
Turnaround: 1-3 weeks for the majority of tests from Monday
24th October
The attached order form will only be accepted at the GCCF Supreme Cat Show 2022.
If you have any questions, please email info@laboklin.co.uk or ring 0161 2823066.
We look forward to seeing you
Kind regards
The Laboklin Team
LABOKLIN (UK)
Laboratory For Veterinary
Diagnostics
125 Northenden Road
Manchester
M33 3HF
Tel: 0161 282 3066
Fax: 0161 973 3434
www.laboklin.co.uk
www.facebook.com/Laboklin
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new
news about genetic blood groups in cats
We are pleased to announce that Nadine has written a very interesting article about blood groups in cats which discusses the different blood groups in cats and how to avoid the risks involved in breeding incompatible blood types. You can download the full article from the following link:
Feline Blood Groups by Nadine Gaenstaller, Laboklin / June 2022
A recent study at Laboklin identified a number of new 'b' variants involved in determining the different blood groups in cats. Our Genetic Blood Group DNA test has now been updated with the new variants and as a result we can now screen all cat breeds except Domestic Shorthair for genetic blood groups. The updated test can detect the 'b' mutation which is reposnible for blood group 'B' more accurately than before and in more breeds, and the 'c' mutation which is repsonsible for blood group 'AB' in Ragdoll and Bengal can now be detected.
The test is valid for all cat breeds except: Domestic Shorthair.
The new improved test is more comperhensive than any other commercially available tests.
Genetic Blood groups in cats
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new
Cone Degeneration ( CD )
Cone degeneration (cd ) is an autosomal recessive disease affecting the German Shorthaired Pointer breed and characterized by day-blindness and absence of retinal cone function in adults. It?s symptoms are similar to the human achromatopsia.
The disease is caused by a mutation in the CNGB3 gene, which leads to Cone Degeneration (CD), which is a disease of the retina. In affected puppies cone cells start to degenerate in the puppy-stage, leading to a distinct form of day blindness. First symptoms can be recognised at the age of about 8-12 weeks. Affected puppies avoid bright light and can be painful. Vision in dim light conditions or at night stays normal. Symptoms continues to worsen as cone cell degeneration progresses over time.
cost £48.00
more information is
available on the following link:
Cone Degeneration ( CD ) in German Shorthaired Pointer (GSP) |
new
Mitochondrial Fission Encephalopathy (MFE) / Familial Cerebellar Ataxia
Mitochondrial Fission Encephalopathy (MFE) Mitochondrial Fission Encephalopathy (MFE) is also known as Cerebellar Ataxia, Familial Cerebellar Ataxia, Progressive Neuronal Abiotrophy (Ataxia) Mitochondrial Fission Encephalopathy (MFE) is a genetic disorder affecting the Bulllmastiff breed and characterised by ataxia, hypermetria, conscious proprioceptive deficits, behavioural abnormalities, and a visual deficit. Symptoms start early in life when the pups are 6-16 weeks old and include visual impairment unsteady gait, uncoordinated movement, stiffness in the muscles of the back legs, bizarre behavioural changes and eventually puppies become unable to stand, and euthanasia is usually carried out as a result of continued deterioration and unresponsiveness to treatment. Histological examination revealed that pathological changes were confined to the brains of the affected animals. A mild to moderate degree of hydrocephalus was present in each case.
Mode of inheritance is autosomal recessive which means that two copies of the mutations (one from each parent) are required to cause the disease. Carriers are not at risk of developing the disease but s
hould only be bred with clear dogs.
A DNA test is now available at Laboklin and will help breeders in controlling the variant in the breed.
A test is now available at
Laboklin cost
£48.00
more information is
available on the following link:
Mitochondrial Fission Encephalopathy (MFE) / Familial Cerebellar Ataxia
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new
MCAD deficiency (MCADD)
Medium chain acyl-CoA dehydrogenase deficiency (MCADD), a fatty acid oxidation disorder, is an inherited disease affecting the CKCS breed. This condition prevents the normal use of fat as an alternative source of energy during times of fasting or increased metabolic demands. Affected animals cannot burn fat for energy when their bodies run out of glucose, and as a result they may be affected by low blood sugar, altered central nervous system function, coma, or sudden death. With an early diagnosis, MCADD can be managed successfully by diet.
In a recent study, affected dogs showed complex focal seizures with prolonged lethargy, lower responsiveness and proprioceptive ataxia. These conditions occurred several times a week and lasted from 20 minutes up to 24 hours. Urine and blood analysis showed an elevated level of medium chain fatty acids. The symptoms improved under medical treatment and diet change towards low fat diet leading to several month without major seizures. The allele frequency within the CKCS population tested in the publication was 23.5%, which means that 5.52% of the tested CKCS were affected.
A DNA test is now available at Laboklin and will help breeders in controlling the variant in the breed.
cost
£48.00
more information is
available on the following link:
MCAD deficiency (MCADD)
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update
Curly coat test has now been updated (C1 + C2)
Hew Curly coat variant (c2) has been identified
A new variant that is responsible for curly coat has been identified and it is named C2. ALthough the C2 variant has been found in few breeds (Curly Coated Retriever, Chesapeake Bay Retriever, Lagotto Romagnolo, Spanish Water Dog, Bichon Frise and Irish Terrier), the test is new and we don't know about its prevalence in other breeds, and therefore we added this variant to our curly coat test which now includes both C1+C2 at no additional cost.
A test is now available at
Laboklin cost
£48.00 for both C1 + C2 if
ordered on its own
£24 for both C1
+ C2 if ordered as
additoinal coat colour test *
more information is
available on the following link:
* if you order more than one
coat colour test at the same
time, you pay full price for
first coat colour test and then
half price for each additional
coat colour / trait test .
Curly Coat: c1 + c2
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new
MDR1 Gene Defect has now been identified in cats
A new test developed by Washington State University researchers can detect a rare genetic mutation in cats that can cause potentially deadly reactions to some common medications, including those used to control parasites and in routine surgical procedures, like spays and neuters.
The only way to tell if a cat has the mutation, which is found in about 4% of all cats, is through a genetic test, which is available to pet owners and vets at Laboklin.
Katrina Mealey is also responsible for the initial discovery of the MDR1 mutation in dogs in 2001 and for leading the development at WSU of the first commercial tests for canines.
'The mutation is probably about as common in cats as it is dogs, except that in dogs we know it is more breed specific,' Mealey said. 'So, if you have a collie, we know the animal has a 75% chance of having the mutation. In cats, though, it seems to be widely distributed and not breed specific.'
cost £48.00
each
more information is
available on the following link:
MDR1 in Cats
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update
Sphynx DNA bundle has now
been updated
The
bundle now includes the
following tests
-
Hypokalemia
/ Familial
Episodic
Hypokalaemic
Polymyopathy
(BHK)
-
Congenital
Myasthenic
Syndrome
(CMS) /
Hereditary
Myopathy
- HCM4
(
Hypertrophic
Cardiomyopathy
HCM 4) in
Sphynx
cost £66.00
more information is
available on the following link:
Sphynx DNA bundle |
More coat colour tests for cats
The following Coat colour tests are now available in cats:
As always if you order more than one coat colour, you pay full price for first coat colour and then half price for each additional coat colour
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feline DNA
bundles
more feline DNA bundles are
now available
We continue to expand our
range of breed specific DNA
bundles for cats to cover more
breeds. Each bundle includes the
most relevant DNA tests for the
breed at a discounted price.
more bundles available on the
following link
Genetic Diseases in cats
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testing is easy
To test an animal, we need a DNA sample, which can be collected using simple mouth swabs or a blood sample collected by the vet. Both buccal swabs and blood tubes are available from us free of charge. Samples can be sent to our Manchester address below.
Turnaround 2-3 weeks or sooner for most DNA test.
Request Sample Materials
LABOKLIN is a DIN EN ISO / IEC 17025 Accredited laboratory. This means that all our tests are performed according to the reliable accreditation standards and verified procedures.
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LABOKLIN
(UK),
125
Northenden
Road,
Manchester,
Greater
Manchester,
M33
3HF,
United
Kingdom
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