We are pleased to announce that LABOKLIN will be at the GCCF Supreme Cat Show on Saturday 21st October 2023 and we look forward to seeing you there.
Meet the experts
We are pleased to announce that our feline genetics expert Nadine Gänstaller
will be at the show and will be very pleased to answer any questions or queries you have.
We always talk on the phone, by email or even via facebook, however, at the GCCF we are very excited to meet you in person and to answer any questions you have, please stop by and say hi.
The Show offer
10% discount on all DNA tests submitted at the GCCF Supreme Cat Show! and this offer includes our Breed Specific DNA Bundles which are already heavily discounted.
How to submit a sample at the GCCF show:
Bring your cat to our stand: we will take a DNA sample for your genetic test, all you need to do is complete the order form and pay the fees. Or,
If you don't want to wait in the queue, or if you are attending the show without your cats, you can prepare your sample in advance and bring it together with the attached order form with you to our stand. You can order a free DNA testing kit on our website, click on the following link to order:
We will send you a testing kit which also contains
order form and instructions on how to take DNA sample from the mouth. Prepare your sample up to a week before your planned visit, just hand the sample to us at the show.
If you prefer to use blood for your test, ask your vet to collect 0.5-1 ml of whole blood in EDTA blood tube, bring it together with the completed order form
(click
here to download the show discounted form) to the show, just hand it to us. (you can order free EDTA blood tube from our website http://www.laboklin.co.uk )
Please note we will only accept Cash, Cheques or Postal Orders at the show. If you wish to pay by card, you can complete the card payment section on the order form. Paypal payments must be made in advance.
Turnaround: 1-3 weeks for the majority of tests from Monday
23rd October
The attached order form will only be accepted at the GCCF Supreme Cat Show 2023.
If you have any questions, please email info@laboklin.co.uk or ring 0161 2823066.
We look forward to seeing you
Kind regards
The Laboklin Team
LABOKLIN (UK)
Laboratory For Veterinary
Diagnostics
Unit 20
Wheel Forge Way
Trafford Park
Manchester
M17 1EH
our most
comprehensive feline genetic
bundle at discounted price
Coming soon, our Feline XXL DNA bundle is a large collection of
genetic tests designed to unlock the secrets of your cat?s health
and other traits. This extraordinary bundle combines a diverse range
of tests carefully selected to reveal fascinating insights about
your cat?s genetic makeup and genetic predispositions. And the best
part? It will be available at a great price.
The new, comprehensive LABOGenetics XXL Cat package
examines over 50 genetic variants . You will
receive information about hereditary diseases, genetic risk factors,
coat colors and coat characteristics. And of course your animal's
genetic blood group shouldn't is of course also included - for cats
of all breeds and mixes!
This new package is of interest to everyone, whether you keep cats,
breed them or are a vet.
For breeders: Make informed breeding
decisions, improve the genetic health of your breed and breed
healthier offspring.
For cat owners: Gain insights into your cat's
genetics and uncover possible health risks.
For vets: Improve your diagnosis and
treatment plans with valuable genetic information, enabling
better care for your cat patients.
For breeding clubs: Provide your club members
with advanced genetic testing and support responsible breeding
practices.
new
Cerebellar Ataxia ( CA1 )
Belgian Shepherd
Cerebellar Ataxia (CA1) is caused by an autosomal recessive
variant in the RALGAPA1 gene, which has been identified in the
Belgian Shepherd breeds.
Affected puppies develop cerebellar dysfunction and are less
active and alert compared to healthy littermates. The puppies
show a wide-based stance and ataxic gait, exaggerated gait
movements as well as stumbling, staggering and intention tremor
of the head. Mild proprioceptive deficits can also be detected
and the occulovestibular response seems to be normal to reduced.
Clinical examinations of cerebrospinal fluid and blood remain
unremarkable.
CA1 has an early onset of around 4 weeks of age, when the
activity and mobility of the puppies increases. In some cases,
the cerebellar symptoms were slowly progressive, requiring the
puppies to be euthanized due to the severity of the symptoms at
the age of 5 weeks. In other cases, the clinical signs were
stable until the age of 11 week and the dogs reached adulthood
without obvious worsening of the symptoms.
cost £48.00
more information is
available on the following link:
MERTKA-PRA is a new and unique form of PRA characterized by the
multifocal appearance of red and brown discoloration of the tapetal
fundus followed over time by thinning of the retina.
Electroretinography revealed a gradual loss of both rod and cone
photoreceptor-mediated function in later stages of the disease. In
the few dogs that suffered from pronounced vision loss,
night-blindness occurred first in later stage, followed by decreased
day-vision in the stage that follows. Histologic examinations
confirmed the loss of photoreceptor cells in the late stage, and
this was associated with the accumulation of autofluorescent
material in the adjacent retinal pigment epithelium
A mutation in the MERTK gene was identified in the Swedish Vallhund
(Västgötaspets) breed which associated with MERTK-PRA. The age of
onset and severity of symptoms varies, and there is a large
variability in the age of diagnosis (as early as 1.1 years and as
late as 12.6 years) have been reported.
cost
£48.00
more information is
available on the following link:
Limb Girdle Muscular Dystrophy (LGMD) is an inherited neuro-muscular
disease affecting Dachshunds. Affected dogs show clinical signs
including exercise intolerance, stiff gait, progressive weakness,
the presence of an excess amount of myoglobin in the urine
(myoglobinuria) which is due to muscle breakdown releasing a high
amount of myoglobin in the blood, as well as difficulty in
swallowing food (dysphagia) and aspiration pneumonia.
Markedly and persistently elevated serum creatine kinase (CK)
activities can be measured in blood examinations. The symptoms
appeared in young adult animals, approximately starting at the age
of 7-17 months.
A mutation in the sarcoglycan alpha subunit (SGCA) gene has been
identified as associated with Limb-Girdle Muscular Dystrophy (LGMD)
in the Dachshund breed..
cost
£48.00
more information is
available on the following link:
more
breeds are now covered by our
popular DNA bundles
We continue to expand our
range of breed specific DNA
bundles for cats to cover more
breeds. Each bundle includes the
most relevant DNA tests for the
breed at a discounted price.
Also known as 'Delayed Bleeding Syndrome or hyperfibrinolysis
Delayed postoperative hemorrhage (DEPOH) is recognized as an
important health problem in certain breeds, including Scottish
deerhounds.
Signs of abnormal bleeding ranged from severe skin bruising around
the surgical site to frank oozing of blood from the wound.
It is important to point out that this is a disorder of clot
stability, not the hemostatic clot formation . In affected dogs,
bleeding is usually (but not always) delayed, typically starting
within 24?48 hours after surgery or major trauma. This is due to
reduced alpha-2 antiplasmin activity (hyperfibinolysis) resulting in
premature lot dissolution.
DEPOH can be prevented or treated with antifibrinolytic drugs such as
EACA (Epsilon-aminocaproic acid) or tranexamic acid.
DEPOH is a totally separate problem from Factor VII Deficiency ? in fact, it is
possible for a dog to be affected with both problems.
cost £48.00
more information is
available on the following link:
Dilated cardiomyopathy is a disease of the heart muscle, which leads to dilation and enlargement of the heart's left ventricle (the heart's main pumping chamber) and consequently the heart becomes weaker and unable to pump blood effectively.
cost £48.00
more information is
available on the following link:
Squamous cell carcinoma of the digit (SCCD) is a breed specific nail bed skin cancer with increased risk found in black dogs such as Standard Poodles and Giant Schnauzers. It is a form of skin cancer; more specifically it is a malignant tumour in the epidermal cells of the skin.
SCCD is strongly association with dark coat colors in a number of breeds. Black Standard poodle dogs are at high risk for SCCD, but light coloured dogs, including white and cream are, known to be, unaffected. Although the light colored Standard Poodles have the causal variant at the same frequency as the black Standard Poodles, they do not get the cancer because it is thought that the mutation that is associated with the light coat colour prevents the SCCD causal variant from increasing risk of SCCD.
Squamous cell carcinomas in dogs often appear as a white skin mass or a raised lump on the skin, in the nail beds of the toes, or in the mouth. The mass may bleed or ulcerate as the condition progresses. In dogs, squamous cell carcinomas are the most frequently diagnosed carcinomas.
At the moment we can only accept blood in EDTA blood tubes for this test - We cannot accept swabs.
cost £48.00
more information is
available on the following link:
Paroxysmal Exercise-Induced Dyskinesia (PED) is a progressive genetic disorder characterised by dyskinetic episodes triggered mainly by exercise and stress. Symptoms include generalised ataxia, lack of coordination and balance resulting in a an exaggerated 'goose-stepping' gait, called hypermetria where the dog overreach the intended location. Increased muscle tone can be seen in all limbs as well as abnormal muscle tone, and mild tremors. In severe cases, the dog will lose its ability to walk. Episodes vary in duration from minutes or hours.
cost £48.00
more information is
available on the following link:
To test an animal, we need a DNA sample, which can be collected using
simple mouth swabs or a blood sample collected by the vet. Both
buccal swabs and blood tubes are available from us free of charge.
Samples can be sent to our Manchester address below.
LABOKLIN is a DIN EN ISO / IEC 17025 Accredited laboratory. This
means that all our tests are performed according to the reliable
accreditation standards and verified procedures.
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LABOKLIN
(UK),
Unit
20,
Wheel
FOrge
Way,
Trafford
Park,
Manchester
M17
1EH,
United
Kingdom
