LABOKLIN (UK)|Pathology | Tumor Genetics| BRAF bundle Comp. (V595E + 2 CAN) (dog)
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BRAF bundle Comp. (V595E + 2 CAN) (dog)

Test number: 518

BRAF + 2 CAN

this is a BRAF bundle Comp. (V595E + 2 CAN)
Species
Dog / Canine .
Description

droplet digital PCR (ddPCR) and copy number alteration (CNA)

Indications:

  • It was not possible to get a reliable histological/cytological diagnosis.
  • Screening for transitional cell carcinoma in certain predisposed terrier breeds (e.g. Scottish Terrier, Fox Terrier, Jack Russell Terrier, West Highland White Terrier)
  • Difficult patient

Method:

droplet digital PCR (ddPCR) and copy number alteration (CNA)

Notes:

  • Detection of BRAF variant V595E and detection of copy number alterations (CNAs) 13/19 and 36/19.
  • Only a positive result is conclusive.
  • Reasons for negative results:
    • The transitional cell carcinoma is not caused by BRAF mutation or the CNAs 13/19 and 36/19.
    • There were no mutated cells present in the sample.
    • It is not a transitional cell carcinoma.
  • The test for CNAs is not suitable for prostate carcinomas.
  • The test cannot be used for cats.

Please note that when you order this analysis 518 BRAF comp. (V595E + 2CNA) test you will be charged full price for the analysis. However, you may order the BRAF mutation on its own and if there is sufficient materials remaining, we will offer you the opportunity to order the 2 CAN as an add on test at additional £159.5 plus VAT.

Sample Requirements
5 - 10 ml urine, formalin fixed tissue, or smears

If urinary bladder/urethral carcinoma (transitional cell carcinoma) is suspected:

  • Urinary sediment (especially early morning urine; fluid + smear)
  • Aspiration cytology (smears)
  • Biopsies (formalin-fixed)
.
Turnaround
2-4 weeks
Price

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  • If you have any queries, please contact us on:
    Tel: 0161 282 3066
    email: info@laboklin.co.uk
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Tel. 0161 282 3066