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PCR
Mycoplasma pulmonis is the causative agent of 'murine respiratory mycoplasmosis' in rats and mice, a slowly progressing infection of the respiratory tracts associated with the formation of thick mucus. Clinical signs of infected animals are sneezing, mucopurulent nasal discharge, stertorous breathing sounds and dyspnoea. The infection can spread to the middle ear and lead to otitis media and head tilt.
In addition, especially in older female rats, Mycoplasma pulmonis can cause genital infection which leads to infertility or a small litter size. In rare cases, metritis or pyometra are also seen.
Latent infections without any clinical signs are common.
Transmission occurs through aerosols in close direct contact. Sexual or intrauterine transmission is also possible.
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Mucous Membranes
Mycoplasma haemotropic
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