Macrothrombocytopenia ( MTC ) is inherited as an autosomal Recessive trait characterized by low platelet count and the presence of some larger than normal platelets in circulation.
Unlike acquired macrothrombocytopenia (thrombocytopenias secondary to infectious agents, medications, immune-mediated causes), this form does not respond to treatment.
It is important to note that these dogs may mistakenly be considered to have an underlying disease that results in thrombocytopenia, such as immune-mediated thrombocytopenia, tick-borne infection, or a bone marrow disorder.
MTC in Cairn Terrier and Norfolk Terrier is inherited as an autosomal recessive trait and results can be Clear (N/N), Carrier (N / MTC), or Affected (MTC / MTC)
A dominant form of MTC is found in other breeds click on the following link for further details: Dominant Macrothrombocytopenia (MTC) .
