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Polycystic Kidney Disease (PKD)
Test number: 8476 (this test number replaces the old 8245D)
Gene: PKD
Price: £ 48.00 (including VAT)
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The Disease |
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polycystic kidney Disease is a genetic slow progressing and irreversible disease charactarised by the presence of cysts in the functional areas of the kidneys,
The size of the cysts varies from 0.5 mm to 2.5 mm. Cysts grow and expand replacing the normal kidney tissue, as a result, the functionality of the kidneys declines, the disease is likely to end with chronic renal failure in middle to old aged dogs. The disease affects both kidneys.
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Clinical Signs |
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Clinical symptoms may not appear in the early stages of the disease but it will appear when the disease progresses, signs include excessive water drinking, loss of appetite, increased urination, weight loss, sporadic vomitting and deppression.
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Description |
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Up until recently BTPKD was diagnosed using renal ultrasonography, however, now a DNA test is available at LABOKLIN, using a simple mouth swabs or blood sample it is possible to identify genetically affected dogs from very young age.
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Trait of Inheritance |
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BTPKD is an autosomal dominant disease with high penetrance, this means that positively affected dogs are highly likely to develop the disease.In this mode of inheritence, dogs who carry only one copy of the mutant gene are likely to develop the disease.
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Inheritance : AUTOSOMAL
DOMINANT
trait
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Price
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£ 48.00 (including VAT)
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