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Naked Foal Syndrome ( NFS )
Test number: 8594
Gene: NFS
Price: £ 48.00 (including VAT)
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Breed
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Akhal Teke ( Akhal-Teke )
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The Disease |
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Naked Foal Syndrome ( NFS ) is a genetic disorder known to affect the Akhal-Tekes breed. The disease is characterised by lack hair in the body, mane and tail, abnormal teeth development, digestive disorders, persistent diarrhea and laminitis-like problems. The disease is always fatal, most foals die within two weeks of birth but some have survived up to two years of age.
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Trait of Inheritance |
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Inheritance : AUTOSOMAL
RECESSIVE
trait
Sire
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Dam
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Offspring
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clear
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clear
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100% clear
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clear
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carrier
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50% clear + 50%
carriers
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clear
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affected
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100% carriers
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carrier
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clear
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50% clear + 50%
carriers
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carrier
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carrier
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25% clear + 25% affected
+ 50% carriers
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carrier
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affected
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50% carriers + 50%
affected
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affected
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clear
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100% carriers
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affected
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carrier
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50% carriers + 50%
affected
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affected
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affected
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100% affected
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Clear
Genotype: N / N [ Homozygous normal ]
The horse is noncarrier of the mutant gene.
It is very unlikely that the horse will develop Naked Foal Syndrome ( NFS ). The horse will never pass the mutation to its offspring, and therefore it can be bred to any other horse.
Carrier
Genotype: N / NFS [ Heterozygous ]
The horse carries one copy of the mutant gene and one
copy of the normal gene.
It is very unlikely that the horse will develop Naked Foal Syndrome ( NFS ) but since it carries the mutant gene, it can pass it on to its offspring with the probability of 50%. Carriers should only be bred to clear horses. Avoid breeding carrier to carrier because 25% of their offspring is expected to be affected (see table above)
Affected
Genotype: NFS / NFS [ Homozygous mutant ]
The horse carries two copies of the mutant gene and
therefore it will pass the mutant gene to its entire offspring.
The horse is likely to develop Naked Foal Syndrome ( NFS ) and will pass the mutant gene to its entire offspring
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Sample Requirements |
Hair Sample from mane with roots (approx 30 hairs) or 1 ml whole blood in EDTA tube.
How to obtain a viable hair sample
Pull around 30 hairs from the mane of the horse with the roots (in faols hair from the tail maybe taken). Wrap the hairs around your finger or a comb, as close as possible to the skin to ensure you obtain the hair roots. Keep dry, put in a bag, label the bag with the horse name, test (s) required. Place in an envelope and send back to us together with the order form. Broken or cut off hair will not be accepted.
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Price
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£ 48.00 (including VAT)
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| See also: |
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